Unscrambling BOTHER gives 53 words. BOTHER is the longest, and BOTHER scores the most at 11 points.
No other single word uses all 6 letters of BOTHER. BOTHER has 6 letters: 2 vowels and 4 consonants, worth 11 points before any board bonuses.
6-letter words 1
5-letter words 5
berth10broth10other8throb10throe8
4-letter words 11
beth9bore6bort6both9herb9hero7hoer7robe6rote4thro7tore4
3-letter words 24
bet5bot5bro5ert3eth6her6het6hob8hoe6hot6obe5orb5ore3ort3reb5ret3rho6rob5roe3rot3the6tho6toe3tor3
2-letter words 12
be4bo4eh5er2et2he5ho5oe2oh5or2re2to2
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.