The letters in COMBINE make 68 words of two letters or more. The longest is COMBINE at 7 letters, and the highest-scoring is COMBINE at 13 points.
No other single word uses all 7 letters of COMBINE. COMBINE has 7 letters: 3 vowels and 4 consonants, worth 13 points before any board bonuses.
7-letter words 1
6-letter words 1
5-letter words 5
biome9bonce9combe11mince9monie7
4-letter words 21
bice8bine6bone6cine6cion6coin6comb10come8cone6coni6ebon6emic8icon6meno6mice8mien6mine6nice6nome6omen6once6
3-letter words 24
ben5bin5bio5cob7con5emo5eon3ice5ion3men5mib7mic7mob7moc7moi5mon5neb5nib5nim5nob5nom5obe5obi5one3
2-letter words 16
be4bi4bo4em4en2in2mb6me4mi4mo4ne2no2oe2oi2om4on2
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.