The letters in ENTIRE make 48 words of two letters or more. The longest is RETINE at 6 letters, and the highest-scoring is ENTIRE at 6 points.
ENTIRE is an anagram of RETINE and TRIENE, using all 6 letters. ENTIRE has 6 letters: 3 vowels and 3 consonants, worth 6 points before any board bonuses.
Anagrams of ENTIRE 2
retine6triene6
6-letter words 3
5-letter words 10
enter5inert5inter5niter5nitre5rente5retie5terne5treen5trine5
4-letter words 12
erne4nite4rein4rent4rete4rite4teen4tern4tier4tine4tire4tree4
3-letter words 15
ere3ern3ert3ire3nee3net3nit3ree3rei3ret3rin3tee3ten3tie3tin3
2-letter words 8
en2er2et2in2it2ne2re2ti2
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.