The letters in EXPLOITS make 223 words of two letters or more. The longest is EXPLOITS at 8 letters, and the highest-scoring is EXPLOITS at 17 points.
No other single word uses all 8 letters of EXPLOITS. EXPLOITS has 8 letters: 3 vowels and 5 consonants, worth 17 points before any board bonuses.
8-letter words 1
7-letter words 4
exploit16exposit16piolets9pistole9
6-letter words 17
extols13ixtles13oxlips15pilose8pilots8piolet8pistol8pixels15poleis8polite8postie8potsie8sexpot15sopite8spoilt8stipel8toiles6
5-letter words 55
estop7exist12exits12expos14extol12islet5istle5ixtle12lexis12lopes7loxes12oxlip14pelts7pesto7piles7pilot7piste7pixel14pixes14plies7plots7poets7poise7poles7polis7posit7poxes14sexto12silex12sixte12slept7slipe7slipt7slope7solei5speil7spelt7spiel7spile7spilt7spite7split7spoil7stile5stipe7stole5stope7teloi5telos5tiles5toile5toils5toles5topes7topis7
4-letter words 73
epos6exit11expo13ilex11isle4leis4lept6lest4lets4lies4lips6lisp6list4lite4lits4lope6lops6lose4lost4loti4lots4oils4oles4opes6opts6oxes11pelt6peso6pest6pets6pies6piet6pile6piso6pits6plie6plot6poet6pois6pole6pols6pose6post6pots6sept6sext11silo4silt4sipe6site4slip6slit4sloe4slop6slot4soil4sole4soli4spit6spot6step6stop6tels4ties4tile4tils4tips6toes4toil4tole4tope6topi6tops6
3-letter words 49
els3its3lei3let3lex10lie3lip5lis3lit3lop5lot3lox10oes3oil3ole3ope5ops5opt5ose3pes5pet5pie5pis5pit5pix12poe5poi5pol5pot5pox12psi5sei3sel3set3sip5sit3six10sol3sop5sot3sox10tel3tie3til3tip5tis3toe3top5xis10
2-letter words 24
el2es2et2ex9is2it2li2lo2ls2lx9oe2oi2op4os2ox9pe4pi4ps4si2so2ti2to2ts2xi9
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.