The letters in INSIST make 25 words of two letters or more. The longest is INSIST at 6 letters, and the highest-scoring is INSIST at 6 points.
No other single word uses all 6 letters of INSIST. INSIST has 6 letters: 2 vowels and 4 consonants, worth 6 points before any board bonuses.
6-letter words 1
5-letter words 2
intis5snits5
4-letter words 7
inti4nisi4nits4sins4sits4snit4tins4
3-letter words 8
ins3its3nit3sin3sis3sit3tin3tis3
2-letter words 7
in2is2it2si2ss2ti2ts2
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.