Unscrambling POSSIBLE gives 167 words. POSSIBLE is the longest, and POSSIBLE scores the most at 12 points.
No other single word uses all 8 letters of POSSIBLE. POSSIBLE has 8 letters: 3 vowels and 5 consonants, worth 12 points before any board bonuses.
8-letter words 1
6-letter words 12
pilose8plisse8poises8poleis8posies8possie8slipes8slopes8speils8spiels8spiles8spoils8
5-letter words 41
biles7bises7bless7blips9bliss7boils7boles7isles5lisps7lobes7loess5lopes7loses5obeli7pesos7piles7pisos7plebs9plies7poise7poles7polis7poses7posse7silos5sipes7slipe7slips7slobs7sloes5slope7slops7soils5solei5soles5speil7speos7spiel7spies7spile7spoil7
4-letter words 56
bels6bile6bios6bise6blip8boil6bole6bops8boss6epos6isle4leis4less4libs6lies4lips6lisp6lobe6lobs6lope6lops6lose4loss4obes6obis6oils4oles4opes6oses4peso6pies6pile6piso6pleb8plie6pois6pole6pols6pose6psis6seis4sels4sibs6silo4sipe6sips6slip6slob6sloe4slop6sobs6soil4sole4soli4sols4sops6
3-letter words 38
bel5bio5bis5bop7bos5els3ess3lei3lib5lie3lip5lis3lob5lop5obe5obi5oes3oil3ole3ope5ops5ose3pes5pie5pis5poe5poi5pol5psi5sei3sel3sib5sip5sis3sob5sol3sop5sos3
2-letter words 19
be4bi4bo4el2es2is2li2lo2ls2oe2oi2op4os2pe4pi4ps4si2so2ss2
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.