The letters in PRESCRIBE make 192 words of two letters or more. The longest is PRESCRIBE at 9 letters, and the highest-scoring is PRESCRIBE at 15 points.
No other single word uses all 9 letters of PRESCRIBE. PRESCRIBE has 9 letters: 3 vowels and 6 consonants, worth 15 points before any board bonuses.
9-letter words 1
8-letter words 3
piercers12preciser12reprices12
7-letter words 16
berries9crepier11crisper11escribe11perries9piecers11piercer11pierces11precise11pricers11prisere9recipes11reprice11reprise9respire9scriber11
6-letter words 23
5-letter words 52
beeps9beers7bicep11bices9biers7birrs7birse7brees7brier7bries7cepes9ceres7cires7creep9crees7crepe9cribs9crier7cries7cripe9crisp9epics9peers7peise7peris7perse7piece9piers7prees7prese7price9prier7pries7prise7rebec9ribes7ricer7rices7riper7ripes7riser5scree7scrip9sepic9serer5siree5speer7speir7spice9spier7spire7spree7
4-letter words 49
beep8beer6bees6bice8bier6birr6bise6bree6brei6brie6bris6cees6cepe8ceps8cere6cire6cree6crib8cris6epic8errs4ices6ires4pecs8peer6pees6peri6pice8pics8pier6pies6pree6rebs6recs6rees4reis4reps6ribs6rice6ripe6rips6rise4seep6seer4sere4sice6sipe6sire4spec8
3-letter words 36
bee5bis5brr5cee5cep7cis5ere3err3ers3ice5ire3pec7pee5per5pes5pic7pie5pis5psi5reb5rec5ree3rei3rep5res3rib5rip5sec5see3sei3ser3sib5sic5sip5sir3sri3
2-letter words 12
be4bi4cs4er2es2is2pe4pi4ps4re2rs2si2
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.