There are 37 words hidden in the letters of SCIENCE, from 7 two-letter words up to SCIENCE (7 letters). For points, SCIENCE is best at 11.
No other single word uses all 7 letters of SCIENCE. SCIENCE has 7 letters: 3 vowels and 4 consonants, worth 11 points before any board bonuses.
7-letter words 1
6-letter words 2
nieces8scenic10
5-letter words 6
cense7cines7niece7scene7seine5since7
4-letter words 8
cees6cine6ices6nice6seen4sene4sice6sine4
3-letter words 13
cee5cis5csc7ens3ice5ins3nee3sec5see3sei3sen3sic5sin3
2-letter words 7
cs4en2es2in2is2ne2si2
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.