The letters in SENSIBLE make 111 words of two letters or more. The longest is SENSIBLE at 8 letters, and the highest-scoring is SENSIBLE at 10 points.
No other single word uses all 8 letters of SENSIBLE. SENSIBLE has 8 letters: 3 vowels and 5 consonants, worth 10 points before any board bonuses.
8-letter words 1
7-letter words 3
enisles7ensiles7seniles7
6-letter words 8
belies8enisle6ensile6lebens8lenses6lessen6seines6senile6
5-letter words 20
belie7benes7biles7bines7bises7bless7bliss7isles5leben7lenes5lenis5lense5liens5lines5seels5seine5seise5sense5sines5snibs7
4-letter words 39
been6bees6bels6bene6bens6bile6bine6bins6bise6blin6eels4else4eses4esse4isle4lees4leis4lens4less4libs6lien4lies4line4lins4nebs6ness4nibs6nils4seel4seen4sees4seis4sels4sene4sens4sibs6sine4sins4snib6
3-letter words 27
bee5bel5ben5bin5bis5eel3els3ens3ess3ins3lee3lei3lib5lie3lin3lis3neb5nee3nib5nil3see3sei3sel3sen3sib5sin3sis3
2-letter words 13
be4bi4el2en2es2in2is2li2ln2ls2ne2si2ss2
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.