The letters in SOMEONE make 72 words of two letters or more. The longest is SOMEONE at 7 letters, and the highest-scoring is SOMEONE at 9 points.
No other single word uses all 7 letters of SOMEONE. SOMEONE has 7 letters: 4 vowels and 3 consonants, worth 9 points before any board bonuses.
7-letter words 1
5-letter words 11
mense7mesne7meson7monos7moons7moose7neems7nomes7nomos7noose5omens7
4-letter words 23
emes6emos6eons4mene6meno6mono6mons6moon6moos6neem6noes4nome6noms6nose4omen6ones4seem6seen4seme6sene4some6sone4soon4
3-letter words 23
eme5emo5ems5ens3eon3men5mes5mon5moo5mos5nee3nom5noo3nos3oes3oms5one3ons3ose3see3sen3som5son3
2-letter words 14
em4en2es2me4mo4ms4ne2no2oe2om4on2oo2os2so2
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.