The letters in TROUBLE make 104 words of two letters or more. The longest is TROUBLE at 7 letters, and the highest-scoring is TROUBLE at 9 points.
No other single word uses all 7 letters of TROUBLE. TROUBLE has 7 letters: 3 vowels and 4 consonants, worth 9 points before any board bonuses.
7-letter words 1
6-letter words 4
bolter8brulot8butler8rouble8
5-letter words 18
bluer7bluet7blurt7botel7boule7brute7buret7buteo7butle7outer5outre5rebut7roble7route5rubel7ruble7tuber7turbo7
4-letter words 38
belt6blet6blot6blue6blur6bole6bolt6bore6bort6bour6bout6brut6burl6bute6euro4lobe6lore4lour4lout4lube6lure4lute4orle4robe6role4rote4rotl4roue4rout4rube6rule4tole4tolu4tore4tour4true4tube6tule4
3-letter words 32
bel5bet5bot5bro5bur5but5ert3let3leu3lob5lot3lur3obe5ole3orb5ore3ort3our3out3reb5ret3rob5roe3rot3rub5rue3rut3tel3toe3tor3tub5urb5
2-letter words 11
be4bo4el2er2et2lo2oe2or2re2to2ut2
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.