The letters in COMBINES make 178 words of two letters or more. The longest is COMBINES at 8 letters, and the highest-scoring is COMBINES at 14 points.
No other single word uses all 8 letters of COMBINES. COMBINES has 8 letters: 3 vowels and 5 consonants, worth 14 points before any board bonuses.
8-letter words 1
7-letter words 3
6-letter words 14
binocs10biomes10bonces10cnemis10combes12conies8cosine8eonism8icones8income10minces10monies8oscine8socmen10
5-letter words 32
besom9bices9bines7biome9bison7bonce9bones7cines7cions7coins7combe11combs11comes9cones7cosie7ebons7eosin5icons7mesic9meson7miens7mince9mines7monie7noise5nomes7omens7osmic9scion7scone7since7sonic7
4-letter words 55
bens6bice8bine6bins6bios6bise6bone6cine6cion6cobs8coin6comb10come8cone6coni6cons6ebon6emic8emos6eons4ices6icon6ions4meno6mibs8mice8mics8mien6mine6mise6miso6mobs8mocs8mons6nebs6nibs6nice6nims6nobs6noes4nome6noms6nose4obes6obis6omen6once6ones4semi6sice6sine4snib6snob6some6sone4
3-letter words 50
ben5bin5bio5bis5bos5cis5cob7con5cos5emo5ems5ens3eon3ice5ins3ion3ism5men5mes5mib7mic7mis5mob7moc7moi5mon5mos5neb5nib5nim5nob5nom5nos3obe5obi5oes3oms5one3ons3ose3sec5sei3sen3sib5sic5sim5sin3sob5som5son3
2-letter words 23
be4bi4bo4cs4em4en2es2in2is2mb6me4mi4mo4ms4ne2no2oe2oi2om4on2os2si2so2
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.